cobas® 4800 System

Real-time polymerase chain reaction (PCR) technology system for the detection of mutations in the KRAS,* BRAF and EGFR* genes of tumor samples

The cobas® 4800 System, v2.0 is a real-time PCR system for the detection of mutations in the KRAS, BRAF and EGFR genes of tumor samples. It features manual sample preparation, PCR technology for amplification and detection combined with automated results interpretation and reporting.

Features and Benefits


Streamlined manual DNA sample preparation

The intuitive graphical user interface provides all instructions to operate the system

The unique design provides temperature uniformity to ensure accurate amplification with every sample

Automated results interpretation

Automated, standardized result reports



Workflow simplicity

Results integrity is achieved by using the proprietary AmpErase enzymes for contamination control which help prevent carryover and detection of previously amplified products

Reproducibility is ensured by the unique Therma-Base layer which provides uniform heating and cooling across the entire plate

Lab efficiency is improved by automated result interpretation and reporting